Publication | Closed Access
Efficient Synthesis of Functionalized Thiazoles from Acid Chlorides, Tetramethylthiourea, Ethyl Bromopyruvate, and Ammonium Thiocyanate
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Citations
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References
2008
Year
Ammonium ThiocyanateBioorganic ChemistryEngineeringAcid ChloridesNatural SciencesOrganic ChemistryFour‐component ReactionEfficient SynthesisChemistryFunctionalized ThiazolesNatural Product SynthesisSynthetic ChemistryEnantioselective SynthesisBiomolecular Engineering
Abstract An efficient synthesis of ethyl 2‐(dimethylamino)‐1,3‐thiazole‐4‐carboxylates is described via a four‐component reaction between acid chlorides, tetramethylthiourea, ethyl bromopyruvate, and ammonium thiocyanate.
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