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Synthesis of 1-Substituted 2-[(2<i>S</i>)-2-Pyrrolidinyl]pyridine from L-Proline
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1990
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DerivativesHeterocyclicN-benzylpyrrolidinyl DerivativesOrganic ChemistryStereoselective SynthesisChemistryHeterocycle ChemistryPharmacologyDerivative (Chemistry)Synthetic Chemistry
The synthesis of optically active 2-[(2S)-2-pyrrolidinyl]pyridine from L-proline is reported. This compound can be further alkylated to give the corresponding N-methyl- and N-benzylpyrrolidinyl derivatives.