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Chemical Explorations Driven by an Enchantment With Mitomycinoids - A Twenty Year Account
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1995
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Bioorganic ChemistryImportant Antitumor CompoundsChemical Explorations DrivenSecondary MetaboliteHeterocycle ChemistryChemical BiologyPharmaceutical ChemistryMedicinal ChemistryAnti-cancer AgentRadiation OncologyPharmacologyNatural Product SynthesisTwenty Year AccountHeterocyclicNatural SciencesConsiderable AttentionMedicineImportant DiscoveriesChemotaxonomyDrug Discovery
The mitomycins and mitomycinoids have attracted considerable attention from chemists and biochemists ever since their discovery over twenty years ago. This account highlights the more important discoveries, as well as tribulations, that occurred in our group en route toward the synthesis of these important antitumor compounds.