Reaction of o-aminobenzamide derivatives with ethoxymethylene-malononitrile and its analogue.

Abstract

A new synthetic method of o-aminobenzamide derivatives with ethyl ethoxymethylenecyanoacetate or ethoxymethylenemalononitrile gave high yield of 3, 4-dihydro-4-oxoquinazoline and 3-aryl-3, 4-dihydro-4-oxoquinazoline derivatives, and the mechanism of this synthetic reaction was discussed.