Palladium‐Catalyzed α‐Selective Alkenylation of Imidazo[1,2‐<i>a</i>]pyridines through Aerobic Cross‐Dehydrogenative Coupling Reaction

Abstract

Abstract The palladium‐catalyzed highly regioselective vinylation of imidazopyridines through a cross‐dehydrogenative coupling reaction was developed. The reaction proceeds with the aid of molecular oxygen as the sole oxidant. A series of branched α‐vinylated products were obtained with high efficiency.