A Convenient Synthesis of 1-Substituted1,2,3-Triazoles via CuI/Et₃N Catalyzed ‘ClickChemistry’ from Azides and Acetylene Gas

Abstract

Copper(I)-catalyzed 'click chemistry' using acetylene gas was successfully explored under mild conditions. 1-Substituted-1,2,3-triazoles were conveniently synthesized From the corresponding aromatic and aliphatic azides.