Publication | Closed Access
An Efficient Ultrasound‐Assisted Synthesis of <i>N</i>‐Alkyl Derivatives of Carbazole, Indole, and Phenothiazine
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Citations
25
References
2013
Year
Chemical EngineeringDerivativesEngineeringHeterocyclicSonoelectrochemistryEfficient Ultrasound‐assisted SynthesisSonochemistryAcidic Hydrogen AtomOrganic ChemistryCatalysisChemistryUltrasoundPotassium HydroxideHeterocycle ChemistryUltrasonic IrradiationDerivative (Chemistry)Synthetic Chemistry
Heterocyclic compounds bearing an acidic hydrogen atom attached to nitrogen such as carbazole, indole, and phenothiazine can be efficiently alkylated in DMSO or N , N ‐DMF under ultrasonic irradiation in the presence of potassium hydroxide as a base. In almost all cases, a dramatic reduction of the reaction time results and a clear yield increase accompanied by an improved quality of the products occurs.
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