A Practical Method for Resolution of the Optical Isomers of 2,2′-Dihydroxy-1,1′-binaphthalene

Yasufumi Tamai, Park Heung-Cho, A. Okamura, Sotaro Miyano

Synthesis · 1990 · 26 citations · 0 references

Concepts

Abstract

Inexpensive (R)-(-)-2-aminobutanol is advantageously used for resolution of the optical isomers of 1,1′-binaphthalene-2,2′-diyl hydrogen phosphate, thus providing a practical route to both of the highly pure enantiomers of 2,2′-dihydroxy-1,1′-binaphthalene on a preparative scale.