Publication | Closed Access
IPy<sub>2</sub>BF<sub>4</sub>/HF-Pyridine: A New Combination of Reagents for the Transformation of Partially Unprotected Thioglycosides and <i>n</i>-Pentenyl Glycosides to Glycosyl Fluorides
25
Citations
19
References
2007
Year
New CombinationDerivative (Chemistry)DerivativesEngineeringBiochemistryNatural SciencesIodine MonofluorideChemical DerivativeFluorous SynthesisOrganic ChemistryPartially Unprotected ThioglycosidesChemistryPharmacologyGlycosyl FluoridesSynthetic EquivalentUnprotected Glycosyl FluoridesBiomolecular EngineeringGlycosylation
The combination of bis(pyridinium)iodonium (I) tetrafluoroborate (IPy2BF4), and hydrogen fluoride pyridine (HF-py) forms an iodine monofluoride (IF) synthetic equivalent that can be used in the preparation of partially unprotected glycosyl fluorides from partially unprotected n-pentenyl glycosides and thioglycosides, thus avoiding the need for the protection/deprotection steps normally required in that transformation.
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