Concepedia

A Versatile Synthesis of 3-Substituted Indoles

Alan R. Katritzky, Linghong Xie, Darren J. Cundy

Synthetic Communications · 1995 · 23 citations · 12 references

DOI

Concepts

Abstract

Abstract A variety of 3-substituted indoles are prepared from 1-methyl-3-(benzotriazol-1-ylalkyl)indoles (1), which are readily available either from the condensation of 3-methylindole with N-(benzotriazol-1-ylalkyl)carbamates or from the alkylation and silylation of lithiated 1-methyl-3-(benzotriazol-1-ylmethyl)indole (2).

References

12

Handbook of heterocyclic chemistry

Choice Reviews Online · 2011 · 747 citations

, , +12

Benzotriazole: A novel synthetic auxiliary

Alan R. Katritzky, Gregory J. Hitchings · Tetrahedron · 1991 · 258 citations

, , +9

Novel 5-HT3 antagonists. Indole oxadiazoles

Christopher J. Swain, Robert J. Baker, Clare O. Kneen et al. · Journal of Medicinal Chemistry · 1991 · 167 citations · Full text

, , +8

Carbon dioxide: a reagent for simultaneous protection of nucleophilic centers and the activation of alternative locations to electrophilic attack. V. Activation of the 2-alkyl group of a 2-alkylindole toward proton loss and subsequent electrophilic substitution

Alan R. Katritzky, K. AKUTAGAWA · Journal of the American Chemical Society · 1986 · 56 citations

, , +12

Convenient novel syntheses of 1,1-bis(heteroaryl)alkanes

Alan R. Katritzky, Linghong Xie, Wei Fan · The Journal of Organic Chemistry · 1993 · 47 citations

, , +6