Concepedia

A Facile Route to Cyclic and Acyclic Alkyl-Arginines

Kevin J. Kennedy, Tiberiu L. Simandan, Thomas A. Dix

Synthetic Communications · 1998 · 24 citations · 9 references

DOI

Concepts

Abstract

Abstract Treatment of commercially available alkyl and cycloalkyl thioureas with methyl iodide provides the corresponding S-alkylisothiouronium iodide which reacts directly with ornithine to yield the title compounds.

References

9

N-methylated arginines; A convenient preparation of N-methylarginine

James L. Corbin, Minocher Reporter · Analytical Biochemistry · 1974 · 58 citations

, , +2

PREPARATION AND CHEMISTRY OF Δ<sup>8</sup>-HEXAHYDRO-1,4,8-PYRIMIDAZOLE, Δ<sup>9</sup>-1,5,9-TRIAZABICYCLO(4.4.0)DECENE, AND Δ<sup>9</sup>-1,4,9-TRIAZABICYGLO(5.3.0)DECENE

A. F. McKay, M.-E. Kreling · Canadian Journal of Chemistry · 1957 · 54 citations

, , +8

Sympathetic Nervous System Blocking Agents. Derivatives of Guanidine and Related Compounds<sup>1</sup>

James H. Short, Ursula Biermacher, Daniel A. Dunnigan et al. · Journal of Medicinal Chemistry · 1963 · 41 citations

, , +10

Potent, long-acting luteinizing hormone releasing hormone antagonists containing new synthetic amino acids: N,N'-dialkyl-D-homoarginines

John J. Nestor, R. Tahilramani, Teresa L. Ho et al. · Journal of Medicinal Chemistry · 1988 · 39 citations

, , +11

Amino Acids. II. Synthesis of Cyclic Guanidino Acids<sup>1</sup>

A. F. McKay, Wilfried Hatton · Journal of the American Chemical Society · 1956 · 38 citations

, , +6