Catalytic C-C Bond Formation in Natural Products Synthesis: Highlights From The Years 2000 – 2005

Abstract

The development of new catalytic reactions for C-C bond formation has played a significant role in natural products synthesis. In this article we review catalytic C-C bond formation with respect to the carbon atoms hybridization and the products formed. The reactions of unusual substrates and the development of new reaction conditions and catalyst systems are included. This survey highlights the use of catalysts in natural products synthesis during the years 2000-2005. Keywords: carbon-hydrogen bond insertions, hybridization, Alkylation, Copper-catalyzed cross-coupling, Negishi Coupling, Heck Reaction