Publication | Open Access
A Cytotoxic Lipopeptide from the Sponge-Derived Fungus Aspergillus versicolor
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Citations
15
References
2010
Year
BiosynthesisBioorganic ChemistryHydroxymethylene ProtonsBiochemistryEngineeringNatural SciencesAntifungal AgentCytotoxic LipopeptideCosy CorrelationMolecular BiologyStructure ElucidationOrganic ChemistryAlcohol DehydrogenasesLipopeptidesCarbonyl MetabolismAmino Alcohol Unit
revealed the presence of an amino alcohol unit (Lol, leucine-derived leucinol), com-mon amino acid units (asparagine and glutamine), and a fatty acyl chain (3-hydroxydodecanoic acid). The presence of a leu-cinol (Lol) moiety was apparent from the COSY correlation of the hydroxymethylene protons at δ 3.46 (H-β'), with the
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