Efficient Palladium-Catalysed Enamide Synthesis from Enol Triflates and Enol Tosylates

Michael C. Willis, Gareth N. Brace, Ian P. Holmes

Synthesis · 2005 · 60 citations · 0 references

Concepts

Abstract

Catalysts generated from Pd2(dba)3 and biphenyl ligands 4 and 7 efficiently promote the coupling of amides and carbamates with unactivated vinyl triflates and tosylates, to provide enamides in good to excellent yields. © Georg Thieme Verlag Stuttgart.