Lewis acid promoted conjugate addition of vinylmagnesium bromide to chiral α,β-unsaturated N-acyl oxazolidinones

Evidence for a reversible d, π-complexation, β-cupration sequence in the conjugate addition reaction of Gilman reagents with α,β-enones.

E. J. Corey, Neil W. Boaz · Tetrahedron Letters · 1985 · 300 citations

Enantioselective Synthesis, Engineering, Organic Chemistry +7

Selective Synthesis by Use of Lewis Acids in the Presence of Organocopper and Related Reagents. New Synthetic Methods (61)

Yoshinori Yamamoto · Angewandte Chemie International Edition in English · 1986 · 255 citations

New Synthetic Methods, Enantioselective Synthesis, Biochemistry +12

Lewis acid mediated reactions of organocopper reagents. Entrainment in the conjugate addition to .alpha.,.beta.-unsaturated ketones, esters, and acids via the RCu.cntdot.BF3 system

Yoshinori Yamamoto, Sinichi Yamamoto, Hidetaka Yatagai et al. · The Journal of Organic Chemistry · 1982 · 227 citations

Novel Organocatalysts, Engineering, Biochemistry +14

Asymmetric 1,4-addition of organocuprates to chiral .alpha.,.beta.-unsaturated N-acyl-4-phenyl-2-oxazolidinones: a new approach to the synthesis of chiral .beta.-branched carboxylic acids

Ernesto Nicolás, Keith C. Russell, Victor J. Hruby · The Journal of Organic Chemistry · 1993 · 170 citations

Asymmetric 1,4-Addition, Engineering, Biochemistry +14

RCu.BF3. 3. Conjugate addition to previously unreactive substituted enoate esters and enoic acids

Yoshinori Yamamoto, Kazuhiro Maruyama · Journal of the American Chemical Society · 1978 · 151 citations

Derivative (Chemistry), Enantioselective Synthesis, Engineering +14