Synlett · 2001 · 53 citations · 0 references
Natural SciencesChemical EngineeringChemistryCatalysisInorganic ChemistryOrganic ChemistryCatalyst DesignCatalyst PreparationCatalytic MaterialsCatalytic MechanismsOrganic SynthesisSupported CatalystsAldehydesCatalyst MechanismsChemoselective CatalysisChemoselective CouplingChemoselective FunctionalizationChemoselective SynthesisMild Reaction ConditionsSupported Oxidation Catalysts
Lithium tetrafluoroborate is found to be an efficient catalyst for the chemoselective protection of both aromatic and aliphatic aldehydes as 1,3-oxathiolanes and 1,3-dithianes under mild reaction conditions. Due to the neutral reaction conditions, this method is compatible with acid sensitive substrates.