Synthesis and antimicrobial activities of 2-substituted 12<i>H</i>-chromeno[3,2-<i>e</i>][1,2,4]triazolo[1,5-<i>c</i>]pyrimidines, 3-ethoxycarbonyl-12<i>H</i>-chromeno[3,2-<i>e</i>][1,2,4]triazolo[1,5-<i>c</i>] pyrimidine-2-one and ethyl 2-formylamino- and 2-acetylamino-4<i>H</i>-chromene-3-carboxylates

Abstract

Preparation of 2-substituted 9-(diethylamino)-12-(4-chlorophenyl)-12 H-chromeno[3,2- e][1,2,4]triazolo[1,5- c]pyrimidines is reported. Furthermore, 3-benzylideneamino-5-(4-chlorophenyl)-8-(diethylamino)-4-imino-3,4-dihydro-5 H-chromeno[2,3- d]pyrimidine, 3-ethoxycarbonyl-12 H-chromeno[3,2- e][1,2,4]triazolo[1,5- c]pyrimidine-2-one, ethyl 2-formylamino- and 2-acetylamino-4 H-chromene-3-carboxylates were prepared. Structures of these compounds were established on the basis of IR, UV, 1 H NMR, 13 C NMR and MS data. The new compounds were evaluated for antimicrobial activities.