Simple and Highly Efficient Catalytic Thiocyanation of Aromatic Compounds in Aqueous Media

Abstract

Abstract Two simple, mild, and efficient procedures for the thiocyanation of N‐heterocycles, substituted anilines (electron‐rich and electron‐deficient), and N ‐substituted aromatic amines at room temperature are reported ( Table 3 ). The first uses H 2 O 2 as pollution‐free oxidant and the second H 5 IO 6 ; both with the reagent potassium thiocyanate in H 2 O as solvent. These procedures provided the target thiocyanates after a short reaction time in good to excellent yields and high regioselectivity.