Isocyanatophosphoric Acid Dichloride: A Novel Reagent for the Introduction of a Cyano Group into the Molecules of Electron-Rich Heterocycles and Enamines

Abstract

A new synthetic method is developed which enables a direct one-step introduction of a cyano group into electron-rich heterocyclic systems of the indole, pyrrole, and indolizine series, and also to enamines using isocyanatophosphoryl dichloride.