Amino Alcohol Mediated Enantioselective Addition of 2-Phenylethynylzinc Bromide to Aldehydes - Concepedia

Concepedia

Publication | Closed Access

Amino Alcohol Mediated Enantioselective Addition of 2-Phenylethynylzinc Bromide to Aldehydes

55

Citations

0

References

1990

Year

Gerardo M. Ramos Tombo, Eric Didier, Bernard Loubinoux

2-Phenylethynylzinc BromideEngineeringOrganic ChemistryStereoselective SynthesisChemistryPharmacologyAsymmetric CatalysisLithium SaltSynthetic ChemistryEnantioselective SynthesisBiomolecular EngineeringGood Yields

Abstract

Optically active secondary phenylalkynyl alcohols were obtained in good yields and selectivities via (-)-N-methyl-ephedrine lithium salt mediated addition of 2-phenylethynylzinc bromide to alkyl and aryl aldehydes.