Publication | Closed Access
Selective Deprotection of Isopropyl Esters, Carbamates and Carbonates with Aluminum Chloride
13
Citations
0
References
2001
Year
Chemical EngineeringAluminum ChlorideCarboxylic AcidsEngineeringNovel OrganocatalystsOrganic ChemistryO-isopropyl BondCatalysisChemistryIsopropyl EstersSynthetic ChemistrySelective Deprotection
The O-isopropyl bond of isopropyl esters, carbamates, and carbonates has been effectively and selectively cleaved by treatment with AlCl3 in nitromethane at 0-50 °C to give carboxylic acids, amines, and alcohols, respectively, in good to excellent yields.