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Stereoselective Alkenylation of Activated Olefins via Nickel-Catalyzed Electroreductive Coupling

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1997

Year

Abstract

The nickel-catalyzed electroreductive conjugate addition of (Z)- or (E)-alkenyl halides to electron-deficient olefins in the presence of a sacrificial iron rod as the anode proceeds with complete retention of the stereochemistry of the alkenyl part and affords functionalized isomerically pure (Z)- or (E)-olefins in high yield.