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An approach to the synthesis of novel 11-hydroxyartemisinin derivatives
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1991
Year
Bioorganic ChemistryAntiparasitic AgentMalariaOrganic ChemistryChemistryPharmaceutical ChemistryPotential Antimalarial DrugsMedicinal ChemistryNovel Artemisinin DerivativesNovel 11-Hydroxyartemisinin DerivativesEpoxide VPhytopharmacologyPharmacologyBiomolecular EngineeringNatural SciencesHerb-drug InteractionMedicineDerivative (Chemistry)Synthetic ChemistryDrug Discovery
The conversion of artemisinin ( I ) to the epoxide V and its use for the preparation of novel artemisinin derivatives as potential antimalarial drugs is described.