Highly Regioselective Nucleophilic Carbon−Carbon Bond Formation on Furans and Thiophenes Initiated by Pummerer-Type Reaction

Abstract

[reaction: see text] The reactions of (phenylsulfinyl)furans or -thiophenes with carbon nucleophiles in the presence of trifluoroacetic anhydride allowed the nucleophilic installation of carbon functional groups on the furan and thiophene nuclei with complete regioselectivity.