Journal of Natural Products · 1995 · 78 citations · 0 references
Life SciencesMedicinal ChemistryPharmacologyCoral Reef BiologyMarine ToxicologyPhycologyMarine Natural ProductsReef-building CoralsBioactive Compounds From Marine CoralsResearch ArticlesSoft Coral BiologySoft Coral MetabolitesSoft Corals As Drug Sources
Bioactivity-guided fractionation of a chloroform extract of the soft coral Simularia gibberosa afforded a new cytotoxic cembranoid diterpene, sinugibberol [1]. The structure of 1 was determined by spectral and X-ray crystallographic analysis.