Sinugibberol, a New Cytotoxic Cembranoid Diterpene from the Soft Coral Sinularia gibberosa

Abstract

Bioactivity-guided fractionation of a chloroform extract of the soft coral Simularia gibberosa afforded a new cytotoxic cembranoid diterpene, sinugibberol [1]. The structure of 1 was determined by spectral and X-ray crystallographic analysis.