Concepedia

Reaction of Halothane with sec-butyllithium in the presence of zinc halides—one-pot preparation of chlorodifluorovinylzinc reagent and its derivatization to α-chloro-β,β-difluorostyrene

Masakazu Nishihara, Yuki Nakamura, Naoki Maruyama, Kazuyuki Sato, Masaaki Omote, Akira Ando, Itsumaro Kumadaki

Journal of Fluorine Chemistry · 2003 · 13 citations · 10 references

DOI

Concepts

References

10

Fluorovinylzinc Reagents: Access to Fluorovinyl Ketones, Esters, and Heterocycles

J. P. Gillet, R. Sauvêtre, J. F. NORMANT · Synthesis · 1986 · 83 citations

, , +8

Synthesis of selectivity fluorinated substrates via organometallic reagents derived from CF2CFCl, CF2CCl2, CF2CH2

Jean‐F. Normant · Journal of Organometallic Chemistry · 1990 · 62 citations

, , +5

Synthesis of fluorinated analogs of natural porphyrins potentially useful for the diagnosis and therapy of cancer

Itsumaro Kumadaki, Akira Ando, Masaaki Omote · Journal of Fluorine Chemistry · 2001 · 30 citations

, , +7

The room temperature preparation of the 1-chloro-2,2-difluorovinylzinc reagent from HCFC-133a (CF3CH2Cl). The first ambient, high yield, one-flask preparation of α-chloro-β,β-difluorostyrenes

R. Anilkumar, Donald J. Burton · Tetrahedron Letters · 2002 · 25 citations

, , +1

A method for synthesis of fluorine compounds using abnormal Grignard reaction of halothane

Toshiyuki Takagi, A. Takesue, Mayumi Koyama et al. · The Journal of Organic Chemistry · 1992 · 24 citations

, , +7