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A Simple and Convenient Synthesis of N-Formyl Amino Acid Esters Under Mild Conditions
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1996
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Room TemperatureEngineeringBiochemistryNatural SciencesDiversity-oriented SynthesisMild ConditionsCyanomethyl FormatePeptide SynthesisOrganic ChemistryConvenient SynthesisSynthetic ChemistryBiomolecular EngineeringGood Yields
A variety of amino acid ester hydrochlorides react with cyanomethyl formate at room temperature to give the N-formyl amino acid esters in good yields and without racemization.