Cell fusion potentiates tumor heterogeneity and reveals circulating hybrid cells that correlate with stage and survival

Charles E. Gast, Alain D. Silk, Luai Zarour, +25

Science Advances

Distribution and characterization of microglia/macrophages in human brain tumors

Wolfgang Roggendorf, S. Strupp, Werner Paulus

Acta Neuropathologica

Neuro-oncologyMedicineBrain Tumor BiologyBrain-immune InteractionNeurology +8

Establishment of human microglial cell lines after transfection of primary cultures of embryonic microglial cells with the SV40 large T antigen

Nazila Janabi, Sylviane Peudenier, Bénédicte Héron, +2

Neuroscience Letters

MedicineImmunologyPrimary CulturesAutoimmunityBrain-immune Interaction +6

The mTOR kinase inhibitor rapamycin decreases iNOS mRNA stability in astrocytes

Lucia Lisi, Pierluigi Navarra, Douglas L. Feinstein, +1

Journal of Neuroinflammation

Expression of iNOS, CD163 and ARG-1 taken as M1 and M2 markers of microglial polarization in human glioblastoma and the surrounding normal parenchyma

Lucia Lisi, Gabriella Maria Pia Ciotti, David J. Braun, +8

Neuroscience Letters

InflammationNeuro-oncologyMicroglial PolarizationGliomaM2 Markers +9

Compensatory glutamine metabolism promotes glioblastoma resistance to mTOR inhibitor treatment

Kazuhiro Tanaka, Takashi Sasayama, Yasuhiro Irino, +14

Journal of Clinical Investigation

mTOR phosphorylated at S2448 binds to raptor and rictor

Margit Rosner, N. Siegel, Alessandro Valli, +2

Amino Acids

Signal TransductionNatural SciencesMolecular BiologyProtein TransportCellular Biochemistry +3

Involvement of mTOR kinase in cytokine-dependent microglial activation and cell proliferation

Cinzia Dello Russo, Lucia Lisi, Giuseppe Tringali, +1

Biochemical Pharmacology

InflammationCytokineSignal TransductionMedicineReceptor Tyrosine Kinase +11

Immunohistologic Evaluation of the Lymphoreticular Infiltrate of Human Central Nervous System Tumors2

Gary W. Wood, Robert A. Morantz

JNCI Journal of the National Cancer Institute

Proinflammatory-Activated Glioma Cells Induce a Switch in Microglial Polarization and Activation Status, From a Predominant M2b Phenotype to a Mixture of M1 and M2a/B Polarized Cells

Lucia Lisi, Egidio Stigliano, Libero Lauriola, +2

ASN NEURO