Synthesis of Oxazoles and Thiazoles Using Thioimidates - Concepedia

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Synthesis of Oxazoles and Thiazoles Using Thioimidates

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1994

Year

Masataka Yokoyama, Yasuhiro Menjo, Mikari Watanabe, Hideo Togo

Acid HalidesThiazoles Using ThioimidatesBioorganic ChemistryDiethyl OxalateNatural SciencesOrganic ChemistryChemistrySeveral OxazolesSynthesis MethodPharmacologySynthetic ChemistryNatural Product Synthesis

Abstract

Several oxazoles and thiazoles were synthesized easily by the reaction of N-(methylthioalkylidene)glycine ethyl ester with diethyl oxalate, acid halides, and thionesters in the presence of base.