Synthesis and psychotropic properties of 1‐triorganylsiloxy‐ and 1‐triorganylgermoxy‐germatranes

Abstract

Abstract Triorganylsiloxy‐ and triorganylgermoxy‐germatranes have been prepared by the interaction of the easily available 1‐hydroxygermatrane with various hetaryl‐silanes and ‐germanes. The compounds were of the general structure: magnified image M = Si; X = S, CH = CH (viz. phenyl); n = 0,1,2 M = Ge; X = CH = CH (viz. phenyl); n = 0 All siloxy‐ and germoxy‐germatranes obtained were subjected to psychotropic assays. Some of phenylsiloxygermatranes are effective for memory enhancement (inhibition of retrogradal amnesia by triphenylsiloxygermatrane was 80%).