Interest in Switching to On-Demand HIV Pre-Exposure Prophylaxis (PrEP) Among Australian Users of Daily PrEP: An Online Survey

Abstract

We surveyed 970 PrEPX study participants to evaluate interest in switching from daily to on-demand PrEP in a study setting. Interested respondents (n = 469, 48%) more commonly reported PrEP cessation (adjusted odds ratio [aOR], 3.0; <i>P</i> < .001), difficulty with adherence (aOR, 1.6; <i>P</i> = .029), infrequent sex (aOR, 3.7; <i>P</i> < .001), and toxicity concerns (aOR, 2.7; <i>P</i> < .001).