Chiral Bis(<i>N</i>-tosylamino)phosphine- and TADDOL-Phosphite-Oxazolines as Ligands in Asymmetric Catalysis

Abstract

A series of P,N-ligands containing a chiral oxazoline ring and a chiral bis(N-tosylamino)phosphine group derived from a 1,2-diamine or a chiral cyclic phosphite group derived from TADDOL has been prepared. These compounds proved to be efficient ligands for enantiocontrol of palladium-catalyzed allylic alkylations and iridium-catalyzed hydrogenations of olefins.