HClO4-SiO2 and NaHSO4-SiO2: Two Efficient Heterogeneous Catalysts for Synthesis of N-Acylsulfonamides under Solvent-free Conditions

Abstract

A simple and efficient synthesis of N-acylsulfonamides has been accomplished by the reaction of sulfonamides with anhydrides under solvent-free conditions in the presence of HClO4-SiO2 or NaHSO4-SiO2. Keywords: N-acylation, N-acylsulfonamide, heterogeneous catalysts, NaHSO4-SiO2, HClO4-SiO2, solvent-free