Comparison of Whole-Body DWI and ¹⁸F-FDG PET/CT for Detecting Intramedullary and Extramedullary Lesions in Multiple Myeloma

Abstract

For detecting intramedullary lesions, WB DWI is more sensitive than PET/CT in all regions except the skull, both in patients with a new diagnosis and previously treated patients and especially in patients with a low percentage of plasma cells. For detecting extramedullary lesions, WB DWI has sensitivity equivalent to that of PET/CT. The use of both modalities may offer complementary information.