Concepedia

Publication | Closed Access

Association of TLR4 with Alzheimer's disease risk and presymptomatic biomarkers of inflammation

DOI

35

Citations

41

References

2019

Year

Justin Miron, Cynthia Picard, Marie‐Élyse Lafaille‐Magnan, Mélissa Savard, Anne Labonté, John C.S. Breitner, Pedro Rosa‐Neto, Daniel Auld, Judes Poirier
Alzheimer s & Dementia

Abstract

The rs4986790 G coding variant in the TLR4 gene appears to reduce AD risk through the modulation of IL-1β synthesis and secretion in the presymptomatic phase of the disease.

References

YearCitations

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