Antimicrobial Blue Light Inactivation of <i>Neisseria gonorrhoeae</i>: Roles of Wavelength, Endogenous Photosensitizer, Oxygen, and Reactive Oxygen Species

Abstract

aBL at 405-nm wavelength is more effective than 470-nm wavelength in inactivating N. gonorrhoeae while sparing the vaginal epithelial cells. Reactive oxygen species generated from the photochemical reactions between aBL and endogenous photosensitizers play a vital role in the anti-gonococcal activity of 405-nm aBL. Lasers Surg. Med. © 2019 Wiley Periodicals, Inc.