Modular, tissue-specific, and biodegradable hydrogel cross-linkers for tissue engineering

Jason L. Guo, Y. S. Kim, Virginia Y. Xie, Brandon T. Smith, Emma Watson, Johnny Lam, Hannah A. Pearce, Paul S. Engel, Antonios G. Mikos

Science Advances · 2019 · 106 citations · 36 references

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Concepts

Abstract

-isopropylacrylamide) to produce rapidly cross-linking, highly swollen, cytocompatible, and hydrolytically degradable hydrogels suitable for mesenchymal stem cell encapsulation. These favorable properties, combined with PdBT's modular design and ease of functionalization, establish strong potential for its usage in tissue engineering applications.

References

36