A Simple RNA Target Capture NGS Strategy for Fusion Genes Assessment in the Diagnostics of Pediatric B‐cell Acute Lymphoblastic Leukemia

Andrea Grioni, Grazia Fazio, Silvia Rigamonti, Vojtěch Bystrý, Giulia Daniele, Zuzana Dostálová, Manuel Quadri, Claudia Saitta, Daniela Silvestri, Simona Songia,

HemaSphere · 2019 · 19 citations · 34 references

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Abstract

rearrangements) in the remaining 38 investigated samples, of which 16 fusion genes had prognostic significance. Herein, we describe the OP and its deployment into routine ALL diagnostics, which will allow substantial improvements in both patient risk stratification and precision medicine.

References

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