Field-Induced Diastereomers for Chiral Separation

Abstract

A novel approach for the state-specific enantiomeric enrichment and the spatial separation of enantiomers is presented. Our scheme utilizes techniques from strong-field laser physics-specifically an optical centrifuge in conjunction with a static electric field-to create a chiral field with defined handedness. Molecular enantiomers experience unique rotational excitation dynamics, and this can be exploited to spatially separate the enantiomers using electrostatic deflection. Notably, the rotational-state-specific enantiomeric enhancement and its handedness are fully controllable. To explain these effects, the conceptual framework of field-induced diastereomers of a chiral molecule is introduced and computationally demonstrated through robust quantum-mechanical simulations on the prototypical chiral molecule propylene oxide (C_{3}H_{6}O), for which ensembles with an enantiomeric excess of up to 30% were obtained.