Concepedia

Use of whole-genome sequencing to guide a <i>Clostridioides difficile</i> diagnostic stewardship program

Kunal Jakharia, Ghassan Ilaiwy, Siobhan Moose, Masashi Waga, Lakshmi Appalla, Joel McAlduff, Lynne V. Karanfil, Patrick McGann, Glenn Wortmann

Infection Control and Hospital Epidemiology · 2019 · 11 citations · 9 references

Abstract

Whole-genome sequencing (WGS) has yielded new insights into the transmission patterns of healthcare facility-onset Clostridioides difficile infection (HO-CDI). WGS results prompted a focused diagnostic stewardship program, which was associated with a significant and sustained decrease in HO-CDI at large, urban hospital.

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