Publication | Open Access
Immunotherapy improves sleep and cognitive impairment in anti-IgLON5 encephalopathy
33
Citations
6
References
2019
Year
Sleep DisordersImmunologyBreathing DisordersImmunotherapyAutoantibodiesNeurologyNeuroimmunologySleepAutoimmune DiseaseAllergyAutoimmune EncephalopathyImmunoglobulin GAutoimmunityBrain-immune InteractionImmunologic DiseaseInsomniaSleep Disordered BreathingSleep DisorderAutoantibody ProductionAnti-iglon5 EncephalopathyImmunoglobulin ESleep ApneaMedicine
Autoimmune encephalopathy associated with immunoglobulin G (IgG) autoantibodies binding to IgLON5 is characterized by a sleep disorder that includes sleep-disordered breathing and parasomnia, accompanied by gait disturbance, bulbar symptoms, dysautonomia, and cognitive decline.1 The effect of immunotherapy in patients with anti-IgLON5 disease remains unclear.
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