Concepedia

Dynamic of systemic immunity and its impact on tumor recurrence after radiofrequency ablation of hepatocellular carcinoma

Philippe Rochigneux, Jean-Charles Nault, Françoise Mallet, Anne-Sophie Chrétien, Nathalie Barget, Alejandro J. Garcia, Lucie Del Pozo, Valérie Bourcier, Lorraine Blaise, Véronique Grando–Lemaire,

OncoImmunology · 2019 · 51 citations · 39 references

DOIFull text

Open access

Concepts

Abstract

: Percutaneous RFA of small HCC leads to systemic modifications of innate and adaptive immunity closely linked with overall tumor recurrence.

References

39

EASL–EORTC Clinical Practice Guidelines: Management of hepatocellular carcinoma

Journal of Hepatology · 2012 · 5.2K citations

, , +12

Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial

Anthony B. El-Khoueiry, Bruno Sangro, Thomas Yau et al. · The Lancet · 2017 · 4.3K citations · Full text

, , +13

Regorafenib for patients with hepatocellular carcinoma who progressed on sorafenib treatment (RESORCE): a randomised, double-blind, placebo-controlled, phase 3 trial

Jordi Bruix, Shukui Qin, Philippe Merle et al. · The Lancet · 2016 · 3.7K citations · Full text

, , +8

NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control

Jan P. Böttcher, Eduardo Bonavita, Probir Chakravarty et al. · Cell · 2018 · 1.8K citations · Full text

, , +17

Expansion and Activation of CD103+ Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition

Hélène Salmon, Juliana Idoyaga, Adeeb Rahman et al. · Immunity · 2016 · 1.2K citations · Full text

, , +16