A rapid strategy for constructing novel simian adenovirus vectors with high viral titer and expressing highly antigenic proteins applicable for vaccine development

Enzymatic assembly of DNA molecules up to several hundred kilobases

Daniel G. Gibson, Lei Young, Ray-Yuan Chuang et al. · Nature Methods · 2009 · 10.9K citations

Life Sciences, Biochemistry, Molecular Biology +16

Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

Susan Buchbinder, Devan V. Mehrotra, Ann Duerr et al. · The Lancet · 2008 · 1.7K citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +16

An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3.

Andrew J. Bett, Wael Haddara, L. Prevec et al. · Proceedings of the National Academy of Sciences · 1994 · 743 citations

Life Sciences, Biotechnology, Molecular Biology +15

HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case–cohort analysis

M. Juliana McElrath, Stephen C. De Rosa, Zoe Moodie et al. · The Lancet · 2008 · 700 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +14

Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys

Peter Abbink, Rafael A. Larocca, Rafael A. De La Barrera et al. · Science · 2016 · 504 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17