Atorvastatin enhances the therapeutic efficacy of mesenchymal stem cells-derived exosomes in acute myocardial infarction via up-regulating long non-coding RNA H19 - Concepedia

Concepedia

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Atorvastatin enhances the therapeutic efficacy of mesenchymal stem cells-derived exosomes in acute myocardial infarction via up-regulating long non-coding RNA H19

DOI Full Paper Access

370

Citations

42

References

2019

Year

Peisen Huang, Li Wang, Qing Li, Xiaqiu Tian, Jun Xu, Junyan Xu, Yuyan Xiong, Guihao Chen, Haiyan Qian, Chen Jin,

Cardiovascular Research

Abstract

Exosomes obtained from ATV-pretreated MSCs have significantly enhanced therapeutic efficacy for treatment of AMI possibly through promoting endothelial cell function. LncRNA H19 mediates, at least partially, the cardioprotective roles of MSCATV-Exo in promoting angiogenesis.

References

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