Downregulation of the histone methyltransferase SETD2 promotes imatinib resistance in chronic myeloid leukaemia cells

Yaru Sheng, Zhongzhong Ji, Huifang Zhao, Jinming Wang, Chaping Cheng, Weimin Xu, Xue Wang, Yuman He, Kaiyuan Liu, Li Li,

Cell Proliferation · 2019 · 21 citations · 51 references

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Abstract

Our study not only emphasizes the regulatory mechanism of SETD2 in CML, but also provides promising therapeutic strategies for overcoming the imatinib resistance in patients with CML.

References

51