Dynamics of Regulatory Mechanisms of the Human Organism on the Basic Hierarchical Levels of the Organization

Abstract

Based on the methodology of the regulatory, the main methods of mathematical modeling of the regulatory mechanisms of living systems at the molecular-genetic, cellular and organ-tissue levels are presented. The constructed mathematical models of the regulatory of the cardiovascular system, the liver and the thyroid gland are presented in the form of systems of functional-differential equations with delay arguments, and also results of qualitative analysis for these models are obtained. Computer models have been developed for quantitative analysis and assessment of the state of biological systems. The most common regularities in the functioning of systems and various behavioral regimes, such as stationary, self-oscillating, dynamic chaos and a "black hole" are revealed.