Infectious Agents and Cancer · 2019 · 14 citations · 9 references
MedicineOncologyPathologyMolecular EpidemiologyMolecular VirologyVirologyCervical BiopsyCervical CancerHuman Papillomavirus InfectionOncogenic VirusesOropharyngeal CancerSquamous Cell CarcinomaDetectionFormalin-fixed Paraffin-embedded Tissue AnalysisGenotype DistributionHpv EpidemiologyHuman Papillomavirus EpidemiologyHuman Papillomavirus StatusParaffin-embedded Tissue StainingRetrospective Case Study
We carried out a retrospective study on the prevalence of HPV and genotype distribution by nested PCR and nucleotide sequencing analysis, in formalin-fixed, paraffin-embedded biopsies of 135 head and neck cancers (HNC) and 29 cervical cancers received between 2009 and 2017 for diagnosis at the Laboratoire National de Biologie Clinique et de Santé Publique of Bangui, the capital city of the Central African Republic. One oropharyngeal squamous cell carcinoma sample was positive for HPV type 16. The overall HPV prevalence in HNC biopsies was 0.74% (95% CI: 0.0-2.2). Among the 29 cervical cancer samples, 19 (65.5%; 95% CI: 48.2-82.8) were positive for HPV. These results indicate that HNC are infrequently associated with HPV infection in the Central African Republic.
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Human papillomavirus‐active head and neck cancer and ethnic health disparities
Paul Weinberger, Mark A. Merkley, Sunny S. Khichi et al. · The Laryngoscope · 2010 · 57 citations · Full text
The role of human papillomavirus in head and neck cancer in Senegal
Cathy Ndiaye, Laia Alemany, Y. Diop et al. · Infectious Agents and Cancer · 2013 · 44 citations · Full text