Publication | Closed Access
2D green SPPS: green solvents for on-resin removal of acid sensitive protecting groups and lactamization
46
Citations
58
References
2019
Year
Solvent ExtractionPurification MethodChemical EngineeringEngineeringSeparation ScienceGreen MaterialSpps MethodGreen ChemistryWater PurificationSeparation TechnologyAnalytical ChemistryGreen ProcessingSeparation TechniqueAdvanced SeparationGreen SppsGreen SolventsOn-resin RemovalChromatography
An SPPS method for the on-resin removal of acid labile protecting groups using TFA/TIS in EtOAc/MeCN and lactamization with PyBOP/DIEA in NBP/EtOAc is reported.
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