Concepedia

Gpnmb secreted from liver promotes lipogenesis in white adipose tissue and aggravates obesity and insulin resistance

Xuemin Gong, Yunfeng Li, Jie Luo, Jiqiu Wang, Jian Wei, Ju-Qiong Wang, Ting Xiao, Chang Xie, Jie Hong, Guang Ning,

Nature Metabolism · 2019 · 94 citations · 47 references

DOI

Concepts

References

47

Positional cloning of the mouse obese gene and its human homologue

Yiying Zhang, Ricardo Proenca, Margherita Maffei et al. · Nature · 1994 · 13.4K citations

, , +12

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

Pontus Boström, Jun Wu, Mark P. Jedrychowski et al. · Nature · 2012 · 4.7K citations · Full text

, , +16

cDNA Cloning and Expression of a Novel Adipose Specific Collagen-like Factor, apM1 (AdiposeMost Abundant Gene Transcript 1)

Kazuhisa Maeda, Kousaku Okubo, Iichiro Shimomura et al. · Biochemical and Biophysical Research Communications · 1996 · 2.1K citations

, , +11

Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

Guangping Gao, Mauricio R. Alvira, Lili Wang et al. · Proceedings of the National Academy of Sciences · 2002 · 1.5K citations · Full text

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FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis

Ffolliott M. Fisher, Sandra Kleiner, Nicholas Douris et al. · Genes & Development · 2012 · 1.5K citations · Full text

, , +17