Publication | Closed Access
Alanine dosimetry at NPL - the development of a mailed reference dosimetry service at radiotherapy dose levels
29
Citations
3
References
1998
Year
Unknown Venue
Alanine RelativeRadiation ExposurePharmacotherapyTreatment VerificationRadiation TestingRadiation MedicineCalibrationRadiation Therapy PlanningInstrumentationGraphite CalorimeterRadiation ImagingRadiation OncologySimultaneous IrradiationNuclear MedicineRadiologyHealth SciencesRadiation DetectionRadiation TherapyAccelerator Mass SpectrometryMedicineRadiation MonitoringIonizing RadiationDosimetryRadiotherapy Dose LevelsAlanine DosimetryRadiation DoseOncology
In this paper we describe the work that has been carried out at NPL to develop a mailed alanine reference dosimetry service for radiotherapy dose levels. The service is based on alanine / paraffin wax dosimeters produced at NPL. Using a data analysis technique based on spectrum fitting, it has been possible to achieve a precision of dose measurement better than ±0.05 Gy (1 o). A phantom set has been developed for use in high energy photon beams, which enables simultaneous irradiation of alanine dosimeters and ionisation chambers in a well defined geometry. Studies in photon beams of energies between Co-60 and 20 MeV have shown no significant energy dependence (<1%) for alanine relative to dose determination using a graphite calorimeter. Work is underway to extend the service to electron beams, and preliminary results are presented on the direct calibration of alanine in electron beams using a graphite calorimeter.
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